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OTHER
Workshop in Lymphoid Cell Culture, Associated Biomedics
Systems, 1974.
Course in Tumor Biology, Harvard Medical School, 1977.
Lectures in Cancer Biology, Stanford University,
1978-1979.
Industrial Workshop in Chemical Mutagens: Principal and
Methods of Detection, University of Texas Medical Branch, 1980.
MEDICAL SCHOOL INFORMATION
Position in class: Upper 10%
Awards: AOA Scholarship
Positions Held: AOA, Louisiana Stars and Bars Chapter,
Vice-President, 1987-1988
Owl Club President, 1987-1988
Owl Club Class Representative, 1984-1988
Owl Club Class Coordinator, 1984-1985
Owl Club Treasurer, 1985-1986
Student Body Treasurer, 1986-1987
Member Medical School Curriculum Corniniffee, 1986-1988
Tutor in the basic sciences for the Medical Education
Reinforcement and
Enrichment Program
Research: The role of genetics and environment on the
incidence of high risk childhood
leukemias in the Louisiana population.
The use of 6-hydroxydopamine on the cleansing of marrow
from patients with
stage IV neuroblastoma.
The role of immune globulin in the treatment of ITP.
Studies on the pretectal area of the cat.
PROFESSIONAL
CURRENT POSITIONS
Director, Pediatric Hematology/Oncology, Florida
Hospital,
2501 N. Orange Ave., Suite 589, Orlando, Florida, 32804
Phone: (407)303-3080 Effective: July 1, 1993
Adjunct Assistant Clinical Professor of Pediatrics,
University of Florida College of Medicine, Effective: July 1, 1994
Principal Investigator, Pediatric Oncology Group,
Pediatric Hematology/Oncology Program,
Effective: April 1,1995
PREVIOUS POSITIONS
Assistant Clinical Professor of Pediatrics, University
of Florida College of Medicine, July 1993-June 1994
Assistant Professor of Biology, Director of Molecular
Biology Honors Program, Long Island University The Brooklyn Center,
1982-1984.
Research Collaborator, Brookhaven National Laboratory,
Upton, New York, 1982-1984.
Toxicologist II, Stauffer Chemical Company, Farmington,
Connecticut, 1979-1982. Responsibilities included reviewing standard
laboratory operating procedures. Designed and implemented research on
molecular dosimetry and genetic risk estimation, including DNA adduct
separation and quantitation. Directed studies on the interaction of the
agricultural flingicide Captan with cellular DNA in vivo. Developed
DNA-carcinogen/mutagen binding assay utilizing agarose gel electrophoresis
of plasmid PM2 DNA. Constructed Salmonella mutagen tester strains
containing a transposable element in the tryptophan synthetase gene using
recombinant DNA techniques. Studied the relationship of the mobilization
of transposable DNA elements by chemical agents with the carcinogenic
potency of those agents.
Microbiology Consultant, University of Miami Student
Health Center, Coral Gables, Florida, 1975-1976.
Research Assistant, Department of Microbiology,
University of Miami School of Medicine, Miami, Florida, 1974-1976.
Research Assistant, TLC Corporation, Miami, Florida,
1968-1970.
Laboratory Assistant, Department of Pediatrics,
University of Miami School of Medicine, Miami, Florida, 1966-1967.
Participant, Dade County Laboratory Research Program,
Laboratory of Paul M. Tocci, Ph.D., Department of Pediatrics, University
of Miami School of Medicine, Miami, Florida, 1965-1966.
- Executive Core Committee
- Patient Care Monitoring Committee
- Pharmacy and Therapeutics Committee
- Board of Directors; Children's House of Central
Florida
- Pediatric Executive Committee
- Pediatric Quality Assurance Committee
- Medical Advisory Board; Boggy Creek Gang Camp
- Ronald McDonald House, Board Member
Teaching Experience
Introductory Physiology, Biology 112, Long Island
University The Brooklyn Center, 1983.
Molecular Biology, Biology 692, Long Island University
The Brooklyn Center, 1983.
Graduate Genetics, Biology 723, Long Island University
The Brooklyn Center, 1983.
Microbiology, Biology 101, Long Island University The
Brooklyn Center, 1983-1984.
Seminar in Biology, Biology 701, Long Island University
The Brooklyn Center, 1983.
Research Advisor, Summer Student Research Program, New
York Academy of Sciences, 1983.
Research Advisor, Biology Masters' Degree Candidates,
Long Island University The Brooklyn Center, 1983-1984.
Lectures on Chemical Carcinogenesis and Short-Term
Testing. Occupational Medicine Elective, University of Connecticut Medical
School, Farmington, Connecticut, 1982.
Lecturer in Radiology 201: Biological Effects of
Radiation; Genetic Disorde~rs that Affect Radiosensitivity, Stanford
University School of Medicine, Stanford, California, 1978.
Organized Joumal Club for Graduate Students and Research
Fellows, Laboratory of Radiobiology, Department of Physiology, Harvard
University School of Public Health, Boston, Massachusetts,
1976-1978.
Microbiology Laboratory for Nursing Students, University
of Miami, Coral Gables, Florida, 1973-1974.
Microbial Genetics Laboratory, Graduate Course,
Department of Microbiology, University of Miami School of Medicine, Miami,
Florida, 1972-1974.
Lectures in Advanced Microbial Genetics, Department of
Microbiology, University of Miami School of Medicine, Miami~ Florida,
1972-1974.
Medical Microbiology for Freshman Medical Students,
University of Miami School of Medicine, Miami, Florida, 1971-1973.
University Responsibilities at Long Island University:
- Toxicology Curriculum Committee, Schwartz College of
Pharmacy, Long Island University.
- Biotechnology Task Group, Long Island University
multicampus committee.
- Advisory Board, Molecular Biology Honors Program, Long
Island University The Brooklyn Center.
- Curriculum Development and Student Recruitment,
Molecular Biology Honors Program, Long Island University The Brooklyn
Center.
Work in Progress
Case study and literature review of familial
hemophagocytic lymphohistiocytosis for neonatologists.
Previous Research Interests
Studies on the immunophenotype of hemophagocytic
histiocytes in familial and viral associated hemophagocytic syndromes.
The effect of site specific DNA modification on in vitro
mammalian cell DNA replication.
Studies on the possible relationship between chemical
carcinogenic potency and transposon mobilization in Salmonella typhimurium.
Effects of Adrenocorticosteroid Hormones on Herpes
simplex virus infectivity in tissue culture.
Investigations on multiplicity reactivation of
ultraviolet-irradiated Herpes simplex virus in Bloom's Syndrome and normal
human skin fibroblasts.
Studies on the electrophoretic mobility of plasmid DNA
treated in vitro with various chemical mutagens and carcinogens.
Biophysical characterization of DNA repair replication
in ultraviolet light-irradiated cells from a Bloom's Syndrome patient
exhibiting defective multiplicity reactivation of UV-irradiated Herpes
simplex virus.
Host-cell reactivation of far ultraviolet-irradiated
Herpes simplex virus by Bloom's Syndrome and normal human skin
fibroblasts.
Molecular characterization bf host-cell reactivation of
UV-irradiated or chemically-treated Herpes simplex virus: monitoring the
removal of ultraviolet endonuclease sensitive sites from viral DNA in
infected cells.
Studies on DNA polymerase activities present in
chromatin from Ultraviolet-irradiated Herpes virus infected cells.
Molecular characterization of various DNA repair
parameters in a strain of Bloom's Syndrome fibroblasts defective in the
multiplicity reactivation of ultraviolet light-irradiated Herpes simplex
virus.
Studies on cells derived from patients with genetic
syndromes associated with increased chromosome aberrations and a high
incidence of neoplastic disease for their ability to reactivate UV- or
X-irradiated Herpes simplex virus.
Studies on host-cell reactivation of Herpes simplex
virus treated with ultraviolet light or chemical carcinogens/mutagens.
Attempts to correlate survival of long-term cell lines
following nitrogen mustard treatment with cellular DNA repair.
Studies on the indication of Streptococcal bacteriophage
and its possible role in host-cell modification of Streptococcus mutans to
carcinogenicity.
Research and development of thin-layer chromatography
techniques for the identification and quantitation of marijuana and other
abused drugs.
Isolation of RNA from the cerebral cortex of
maze-trained mice.
Studies on the localization of amino acid
neurotransmitters in frog brain.
Professional Organizations
- American Academy of Pediatrics
- American Society of Hematology
- American Medical Association
- Orange County Medical Society
- American Association for Cancer Research
- The Histiocytosis Society
- American Society of Clinical Oncology
- Phi Delta Epsilon Medical Fraternity
- American Society of Pediatric Hematology/Oncology
- Environmental Mutagen Society, 1979-1983
- Genetic Toxicology Association, 1979-1983
- Mutagenesis Association of New England, 1979-1983
- American Society for Microbiology, 1970-1983
- American Association for the Advancement of Science,
1970-1980, 1993-Present
HONORS AND AWARDS
Scholarship Award, American Academy of Pediatrics
Elected to AQA, Medical Honor Society, Membership in
Junior Year of Medical School
AOA Scholarship for outstanding Junior Year Medical
Student
Summer Clinical Oncology Fellowship, American Cancer
Society, 1986
Research Grant, Brooklyn Center Fund for Research in
Health Care, 1983
Travel Award, 6th International Congress of Radiation
Research, Tokyo, Japan, 1979.
Traineeship, Cancer Biology Training Program, Stanford
University, Stanford, California, 1978
PHS Research Fellowship granted by the National
Institute on Aging of the National Institutes of Health, 1976
Teaching Assistantship in Microbiology, University of
Miami School of Medicine, Miami, Florida,
1971
Dade County Federation of Women's Clubs Scholarship,
University of Miami, Coral Gables, Florida, 1968-1970
National Defense Scholarship, Indiana University,
Bloomington, Indiana, 1966
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PUBLICATIONS
Selsky, C.A. and S. Greer, "Host-Cell Reactivation of
UV-Irradiated and Chemically-Treated
Herpes simplex Virus-i by Xeroderma Pigmentosum, XI)
Heterozygotes and Normal Skin
Fibroblasts," Mutation Research, 50:395-405, 1978.
Selsky, C.A., R. Weichselbaum and J.B. Little,
"Defective Host-Cell Reactivation of UV-Irradiated
Herpes simplex Virus by Bloom's Syndrome Skin
Fibroblasts, in DNA Repair Mechanisms, ed.
P.C. Hanawalt, E.C. Freidberg, and C. Fred Fox, Academic
Press, New York. pp.555-558, 1978.
Selsky, C.A., P. Henson, R. Weichselbaum and J.B.
Little, "Defective Reactivation of Ultraviolet Light-Irradiated Herpes
virus by a Bloom's Syndrome Fibroblast Strain," Cancer Research,
39:3392-3396, 1979.
Henson, P., C.A. Selsky and J.B. Little, "Excision of
Ultraviolet Damage and the Effect of Irradiation on DNA Synthesis in a
Strain of Bloom's Syndrome Fibroblasts, vI Cancer Research, 41:760-766,
1981.
Shneider, B., M.D., Selsky, C., M.D., and Komp, D.,
M.D., "Idiopathic Neonatal Iron-Storage
Disease: Clinical Similarity to Hemophagocytic
Lymphohistiocytosis," Gastroenterology
102:1826, 1992.
Shneider, B., M.D., Touloukian, R., M.D., Hajjar, F.,
M.D., Selsky, C., M.D., Ph.D., and Buckley, P., M.D., Ph.D., "Perianal
Ulceration, a novel manifestation of Angiocentric Lymphoma." Digestive
Diseases and Science (In press).
ABSTRACTS AND MEETINGS
Selsky, C.A., and S. Greer, "Host-Cell Reactivation of
Chemically-Treated HSV-1 by Human Skin Fibroblasts," American Society for
Microbiology, New York, 1975.
Selsky, C.A., and S.A. Greer, "Host-Cell Reactivation of
Ultraviolet-Irradiated or N-Acetoxy-2-
Acetylaminofluorene-Treated Herpes simplex Virus,"
American Society for Microbiology, New
Orleans, 1977.
Selsky, C.A., "Repair of Herpes Virus DNA," Third Annual
Main Biomedical Symposium, Orono, Maine, 1977.
Selsky, C.A., P. Henson, R.R. Weichselbaum, and J.B.
Little, "Defective Host-Cell Reactivation of Uv-Irradiated Herpes simplex
Virus by a Bloom's Syndrome Skin Fibroblast Cell Strain," Joumal of
Supramolecular Structure, Supplement 2, pg. 36, 1978.
Selsky, C.A., P. Henson, R.R. Weichselbaum, and J.B.
Little, "Characterization of an HCR Bloom's Syndrome Fibroblast Strain,"
Radiation Research Society, Toronto, Canada, 1978.
Selsky, C.A., "Host-Cell Reactivation as a Probe for
Defective Cellular DNA Repair Mechanisms," Fourth Annual Maine Biomedical
Symposium, Orono, Maine, 1978.
Selsky, C.A., P. Henson, and J.B. Little, "Multiplicity
Reactivation of UV-Irradiated Herpes simplex Virus is Defective in Bloom's
Syndrome Skin Fibroblast Strain GM-1492," Seventh Annual Meeting of the
American Society for Photobiology, Asilomar, California, 1979.
Selsky, C.A., and D.W. Matheson, "Association of
Orally-Administered Captan with Mouse Deoxyribonucleic Acid," Twenty-First
Annual Meeting of the Society of Toxicology, Boston, Massachusetts, 1982.
Selsky, C.A., and D.W. Matheson, "Association of the
Broad-Spectrum Fungicide, Captan, with Mouse Soriiatic DNA," Mutagenesis
Association of New England, Sturbridge, Massachusetts, 1982.
CHAPTERS
Selsky, C.A., and Pearson, H.A.: Cancer; Sports and
Exercise for Children with Chronic Health Conditions, In Press, Ed.
Goldstein B.
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